Baby ELEFANT

Age 0, n=48,762, 240 pairs of twins, babies of Young ELEFANT participants

1 Demographic data from parents and babies at birth

2 Birth weight, term birth, birth defects, delivery method

3 Questionnaire from parents (folic acid intake, smoking, drinking, individual and family disease history, previous history of pregnancy and etc)

4 N/A

5 25 monitoring sites in Tianjin, 2002-2010 (PM10, NO2, SO2), 2014-2017 (PM2.5, PM10, O3, NO2, CO, and SO2

Child and Adolescent ELEFANT

Age range 1-19

Currently in development

Young ELEFANT

Age range 20 to 40, n=366,474

1 Age, gender, marital status, residence address, occupation, education and etc

2 Height, weight, fasting blood glucose, blood pressure, TSH, alanine aminotransferase (ALT), aspartate aminotransferase (AST), serum creatinine, fertility and reproductive health, hormonal measurements, use of contraceptives, pregnancy history, adverse events during pregnancy

3 74 variables for women and 35 for men, that include smoking, drinking, psychological stress, individual and family disease history, previous history of pregnancy, occupational exposures, menarche age, and etc

4 Buffy coat, plasma, and urine from 1830 participants

5 25 monitoring sites in Tianjin, 2002-2010 (PM10, NO2, SO2), 2014-2017 (PM2.5, PM10, O3, NO2, CO, and SO2

Middle-aged ELEFANT

Age range 41-60, n>30,000, every year since 2011

Currently in development

Elderly ELEFANT

Age range over 61, n=6,503, mean age 66 in 2011

1 Age, gender, residence address, education and etc

2 More than 76 variables, that include height, weight, blood pressure (SBP, DBP), fasting blood glucose, complete blood cell count, alanine aminotransferase (ALT), aspartate aminotransferase (AST), serum creatinine, urea nitrogen, thyroid stimulating hormone, waist circumference, lipid levels, electrocardiography, total cholesterol, triglycerides

3 59 variables associated with socio-economic status and 49 variables on lifestyle, that include smoking, drinking, exercise, familial history of disease and etc

4 Buffy coat, serum, plasma from 6503 participants in 2016 and blood from 3000 participants in 2018

5 25 monitoring sites in Tianjin, 2002-2010 (PM10, NO2, SO2), 2014-2017 (PM2.5, PM10, O3, NO2, CO, and SO2

Cancer ELEFANT

Currently in development

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